产品货号:
Z18601
中文名称:
HRAS抗体
英文名称:
Anti-HRAS Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-HRAS Antibody |
指标别名 | C BAS/HAS;C H RAS;C HA RAS1;CTLO;GTPase HRas;H Ras 1;H RASIDX;Ha Ras;HAMSV;HRAS;HRAS1;HRAS-Specific;K RAS;RASH1;Transforming protein p21 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,IHC |
基因名称 | HRAS |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human GTPase HRAS (101-137aa KRVKDSDDVPMVLVGNKCDLAARTVESRQAQDLAR SY),identical to the related mouse and rat sequences. |
实际分子量 | 21KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | GTPase HRas,also known as transforming protein p21,is an enzyme that in humans is encoded by the HRAS gene.This gene belongs to the Ras oncogene family,whose members are related to the transforming genes of mammalian sarcoma retroviruses.The products encoded by these genes function in signal transduction pathways.These proteins can bind GTP and GDP,and they have intrinsic GTPase activity.This protein undergoes a continuous cycle of de- and re-palmitoylation,which regulates its rapid exchange between the plasma membrane and the Golgi apparatus.Mutations in this gene cause Costello syndrome,a disease characterized by increased growth at the prenatal stage,growth deficiency at the postnatal stage,predisposition to tumor formation,mental retardation,skin and musculoskeletal abnormalities,distinctive facial appearance and cardiovascular abnormalities.Defects in this gene are implicated in a variety of cancers,including bladder cancer,follicular thyroid cancer,and oral squamous cell carcinoma.Multiple transcript variants,which encode different isoforms,have been identified for this gene. |
Uniprot ID | P01112 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
基因名全称 | Harvey rat sarcoma viral oncogene homolog |
蛋白名全称 | GTPase Hras |
推荐稀释比 | Western blot(WB) 1:500~2000 Immunohistochemistry in paraffin section (IHC) 1:50~400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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